Georgia Institute Of Technology Laboratory Safety Manual-PDF Free Download

Georgia Institute of Technology Laboratory Safety Manual

2020 | 33 views | 140 Pages | 4.14 MB

in all Georgia Tech laboratories in order to ensure a safe environment in which to work and study for faculty, students, visitors, and staff. New situations and hazards arise in research every day. This manual, therefore, cannot possibly be an all-inclusive list of hazards or



Georgia Institute of Technology
Laboratory Safety Manual
This document is an update to the Georgia Institute of Technology Laboratory Safety Manual
April 29 2013 Edition
The following limited revisions were made
1 Updating all Georgia Tech Environmental Health and Safety contact information
2 Updating the GT EHS website links and attachments
3 Updating information regarding the chemical inventory system Environmental
Health and Safety Assistant implemented in July 2017
4 Updating the SDS references previously recognized as MSDS in compliance with
Globally Harmonized Standard
5 Updating the Nanotechnology and Lab Moving
Approved May 29 2013
Reviewed and Revised July 12 2018
Georgia Institute of Technology
Laboratory Safety Manual
1 INTRODUCTION AND GENERAL ADMINISTRATION 10
ENVIRONMENTAL HEALTH AND SAFETY POLICY 11
Purpose 12
Authority Faculty Led EHS Committees 13
Institute Council for Environmental Health and Safety IC EHS 13
Institutional Animal Care and Use Committee 13
Chemical and Environmental Safety Committee CESC 13
Occupational Health and Safety Committee OHSC 13
Biological Materials Safeguards Committee BMSC 13
Institutional Biosafety Committee IBC 14
Radiation Safety Committee RSC 14
Laser Safety Committee LSC 14
Laboratory Responsibilities 14
Department and School Chairs 15
Principal Investigators PIs 15
Laboratory Users 15
Environmental Health Safety EHS 15
Institute Responses to Unsafe Actions and or Unsafe Conditions in Laboratories 16
Level 1 Imminent Hazard with Potentially Severe Consequences 16
Level 1 Response 16
Level 2 Imminent Hazard with Potentially Serious Consequences 17
Level 2 Response 17
Level 3 Not Imminent Hazard but Potentially Serious Consequences 17
Level 3 Response 18
Level 4 Not Imminent but Potential for Undesirable Consequences 18
Level 4 Response 18
Level 5 Repeat Violations Failure to Correct 18
Level 5 Response 19
Other Circumstances 19
Disciplinary Actions 19
2 DEFINITIONS 20
THE GEORGIA RIGHT TO KNOW LAW 25
Georgia Institute of Technology
Laboratory Safety Manual
Chemical Inventory 25
Chemical Management EHSA 25
Purchasing Acquiring Chemicals 26
Semiannual Inventories Reconciliations 26
Disposing of Chemical Waste 26
Training EHSA Users 26
Regulatory Requirements for EHSA 26
Safety Data Sheets SDSs 27
Procurement of Chemicals 27
3 RESTRICTED PURCHASES CHEMICALS AND
EQUIPMENT 27
4 SIGNAGE 28
Exterior Lab Doors 28
Interior Lab Signage 30
5 CONTAINER LABELS 31
Primary Containers 31
Secondary Containers 31
Vials and Test Tubes Sample Containers 31
Unlabeled Containers 31
6 CONTROLLING CHEMICAL EXPOSURE 32
Chemical Hygiene 32
Exposure Monitoring 33
Chemical Exposure Monitoring 33
Biological Monitoring 33
Georgia Institute of Technology
Laboratory Safety Manual
Engineering Controls 33
Fume Hoods 33
Perchloric Acid Hoods 36
Local Exhaust Ventilation 36
Biosafety Cabinets and Laminar Flow Hoods 38
Ventilated Chemical Storage Cabinets 38
Appropriate Lab Attire 39
Other Recommendations Regarding Lab Clothing 41
Personal Protective Equipment 41
Eye Protection 41
Lab Coats 42
Face Protection 43
Hand Protection 43
Respiratory Protection 45
Administrative Controls 51
7 TRAINING 51
8 GENERAL LAB SAFETY 54
Access to Hand Washing Facilities 54
Emergency Equipment 54
Emergency Exits Means of Egress 54
Fire Extinguishers 54
ABC Extinguishers 55
Carbon Dioxide Extinguishers 55
Met L X Extinguishers 55
Using Fire Extinguishers 55
Spill Kits and Spill Clean Up Procedures 56
Emergency Showers 58
Emergency Eyewashes 58
Personal Conduct 59
Housekeeping 59
Fire Safety 60
Georgia Institute of Technology
Laboratory Safety Manual
Electrical Safety 61
Avoiding Electrical Hazards 61
Gas Cylinder Safety 62
General Rules for Handling Gas Cylinders 63
Receiving Cylinders 63
Cylinder Storage Chemical Compatibility 64
Moving Transporting Cylinders 64
Labeling Cylinders 65
Cylinder Fittings Gas Tubing 65
Regulators 65
Cylinder Use 66
Lecture Bottles 67
Sharps and Glass Disposal 69
Hearing Protection 71
Working Alone 71
Unattended Operations 72
9 LAB INSPECTIONS SELF EHS 73
Chemical Safety Visits Quick Check Inspections 73
General Lab Safety Chemical Safety Comprehensive Inspections 74
Types of Comprehensive Inspections 74
Frequency of Comprehensive Inspections 75
Biological Safety Inspections 75
Radiological Safety Inspections 75
10 VISITORS IN LABORATORIES 76
Visiting Scientists and Students 77
Underage Visitors 77
Visiting Elementary and Secondary School Groups 77
11 EMERGENCY PROCEDURES FIRES SPILLS AND
CHEMICAL EXPOSURES 78
Georgia Institute of Technology
Laboratory Safety Manual
Spill Procedures Major and Minor Incidents 78
Minor Incidents 78
How to Clean Up a Minor Spill 78
Major Incidents 79
Major Incidents what you should do 79
Chemical Exposures 80
Respiratory Exposures 80
Skin Exposures 80
Eye Splash 82
12 HAZARDOUS WASTE 83
EHSA Waste Module 84
Chemical Waste Management 84
Chemical Waste Disposal 85
Solvents and Organics 85
Acids and Bases 85
Highly Hazardous Wastes 86
Waste Accumulation 86
Segregation of Waste 87
Waste Containers 87
Labeling of Waste 87
Used Oil 88
Fluorescent and Other Mercury Containing Light Bulbs 89
Contaminated Equipment 90
Lab Clean Outs 90
Lab Closing 90
13 CHEMICAL STORAGE 91
General Storage Guidelines for Solids and Liquids 92
Segregation and Storage of Chemicals according to Hazard Class 92
Georgia Institute of Technology
Laboratory Safety Manual
Chemical Incompatibility Matrix 93
Flammable and Combustible Liquids 95
Flammable Storage Lockers and Refrigerators 95
Oxidizers 98
Water Reactives 98
Air Reactives Pyrophorics 99
Extremely Toxic Chemicals 99
Peroxide Forming Chemicals 99
Secondary Containment for Liquids 104
Squeeze Bottles Chemical Compatibility 105
Chemical Storage Cabinets 105
Chemical Storage for Gases 106
14 RENOVATIONS REPAIRS AND CUSTODIAL SERVICES IN
LABORATORIES 107
Renovations 107
Repairs and Maintenance of Laboratory Facilities 107
Custodial Services in Laboratories 107
15 PROCESS SPECIFIC HAZARDS 108
Working with Dangerous Gases 108
Working with Highly Reactive Materials 110
Piranha 112
Combustible Explosive Dusts 116
Organometallics and Pyrophoric Chemicals 117
Organic Peroxides and Peroxide forming Chemicals 118
Working with Ether Used as an Anesthetic 119
Oxidizers 120
Polynitro compounds 121
Cryogenic Materials 121
Properties of Common Cryogenic Materials 122
General Rules Regarding Handling of Cryogenic Materials 123
Protective Clothing for Working with Cryogenic Materials 124
Cooling Baths and Dry Ice 124
Liquid Nitrogen Cooled Traps 124
Emergencies Involving Cryogenic Materials 124
Georgia Institute of Technology
Laboratory Safety Manual
Extremely and Highly Toxic Chemicals 125
Hydrofluoric Acid 126
Dangerous Powders 127
Antineoplastic Agents 128
Nano Materials 128
Carcinogens 129
Working with High Pressure Systems 130
Working with Vacuum Systems 131
Distillations 133
Solvent Stills Procedure for Set Up Use and Neutralization 133
Column Purification Systems 136
Magnetic Fields 137
Static Magnetic Fields 137
Sub Radio Frequency Magnetic Fields 137
17 Related Safety Programs 138
Biological Safety 138
Radiological Safety 138
Laser Safety 138
Occupational Health 139
Shipping and Receiving Chemical and Biological Materials 139
Shipping Chemical and Biological Materials 139
Receiving Chemical and Biological Materials 140
Georgia Institute of Technology
Laboratory Safety Manual
1 Introduction and General Administration
Laboratory Safety at the Georgia Institute of Technology Georgia Tech is a multi faceted
program managed by Georgia Tech Environmental Health and Safety EHS and includes
programs in Biological Safety Chemical Safety Hazardous Materials Management Fire
and Life Safety General Safety and Radiological Safety Program elements include but
are not limited to Fume Hood Certifications Biosafety Cabinet Certifications Laboratory
Inspections Laboratory Self Inspections Industrial Hygiene Laser Safety High Magnetic
Field Safety and other programs addressed in this Laboratory Safety Manual Questions
or concerns about safety in Georgia Tech Laboratories can be directed to the
Environmental Health and Safety Personnel at 403 894 4635
https ehs gatech edu contact
Georgia Institute of Technology
Laboratory Safety Manual
GEORGIA INSTITUTE OF TECHNOLOGY
ENVIRONMENTAL HEALTH AND SAFETY POLICY
Ratified by the Institute Council on Environmental Health and
Safety August 2008
Georgia Institute of Technology Georgia Tech is committed to
1 Providing a safe secure and healthy environment for all faculty staff students and
2 Conducting research and educational programs in compliance with applicable
environmental health and safety laws and regulations and
3 Demonstrating leadership in pollution prevention waste reduction and the judicious
use of resources for protection of human health safety and the environment
Guiding Principles
Good environmental health and safety practices including compliance are the responsibility
of every faculty member staff employee student and visitor at Georgia Tech This
responsibility cannot be transferred or delegated
Georgia Tech shall make all reasonable efforts to
1 Protect the health and safety of faculty staff students visitors and the surrounding
2 Provide safe workplaces academic research and administrative
3 Provide information and training to faculty staff students and visitors about potential
environmental health and safety hazards
4 Develop and promote the adoption of environmental health and safety best practices
5 Identify and correct environmental health and safety hazards and encourage the
reporting of hazards and safety related incidents
6 Work cooperatively with the City of Atlanta the State of Georgia and regulatory
agencies to promote a safe and healthy environment and
Georgia Institute of Technology
Laboratory Safety Manual
7 Comply with applicable environmental health and safety laws regulations and
consensus standards
Implementing Authority
The Georgia Tech Institute Council for Environmental Health and Safety is the principal
implementing authority for this policy The Council shall adopt implement and integrate
policies and procedures as developed by compliance oversight and other environmental health
and safety committees at Georgia Tech
The Georgia Tech Office of Environmental Health and Safety is responsible for providing
technical guidance oversight consultation training and specialized services to assist the
Institute community in meeting its public health safety and environmental protection
responsibilities
The purpose of this manual is to provide basic safe operating practices to be applied uniformly
in all Georgia Tech laboratories in order to ensure a safe environment in which to work and
study for faculty students visitors and staff New situations and hazards arise in research
every day This manual therefore cannot possibly be an all inclusive list of hazards or
solutions to hazards found in Georgia Tech laboratories and research stations Instead it is
offered as the foundation and guide to approach new challenges and discover ways of safely
dealing with them
The principles and practices found in this manual apply to all Georgia Tech laboratories
including satellite locations and research stations both in the US and abroad
Georgia Institute of Technology
Laboratory Safety Manual
Authority Faculty Led EHS Committees
Institute Council for Environmental Health and Safety IC EHS
The IC EHS is the over arching faculty led Institute safety oversight Council that coordinates
policy recommendations procedures and practices from each of the Institute s safety related
committees The IC EHS is appointed by the President of Georgia Tech and has the authority
to approve new or change existing procedures with consultation and input from Council
IC EHS membership is comprised of the Chairs of the Institute s other faculty led safety
committees including the Institutional Animal Care and Use Committee IACUC
Institutional Biosafety Committee IBC Biological Materials Safeguard Committee
BMSC Campus Welfare and Security Committee CWSC Chemical and Environmental
Safety Committee CESC Occupational Health and Safety Committee OHSC
Radiological Safety Committee RSC Laser Safety Committee LSC as well as members
from the Office of Research Integrity Assurance the Office of Human Resources Legal
Affairs and Risk Management Student Health Services and EHS The IC EHS reviews the
work of the various campus safety committees and has the authority to recommend
disciplinary action in accordance with Institute procedures for violations of Georgia Tech
safety rules
Institutional Animal Care and Use Committee
This committee constituted in accordance with federal law reviews all proposed research
and teaching activities involving vertebrate animals The IACUC is charged with ensuring
the humane care use and disposition of vertebrate animals involved in teaching and research
activities at Georgia Tech
Chemical and Environmental Safety Committee CESC
The CESC is responsible for reviewing and approving this manual and all safety practices and
policies applied to GT laboratories reviewing recent laboratory incidents communicating
trends and issues to the Georgia Tech IC EHS and to Department Chairs and recommending
changes as needed in GT practices and policies
Occupational Health and Safety Committee OHSC
The OHSC considers and advises EHS and the IC EHS on programs and policies regarding
occupational health and workplace safety at Georgia Tech
Biological Materials Safeguards Committee BMSC
The BMSC considers and advises EHS and the IC EHS on programs and policies regarding
the safe and compliant use of non r DNA biological materials and research protocols at
Georgia Tech
Georgia Institute of Technology
Laboratory Safety Manual
Institutional Biosafety Committee IBC
The IBC reviews all registrations for research teaching and training that involve the use of
rDNA and ensures that the proposed activities comply with federal regulations and Institute
policies The IBC considers and advises EHS and the IC EHS on programs and policies
regarding the safe and compliant use of r DNA biological materials and research protocols at
Georgia Tech
Radiation Safety Committee RSC
The RSC is responsible for maintaining the health and safety standards associated with the
use of radioactive materials and ionizing radiation producing devices at Georgia Tech and
ensuring that research activities conform to State of Georgia Regulations The RSC considers
and advises EHS and the IC EHS on programs and policies regarding the safe and compliant
use of radioactive materials and radiation producing devices at Georgia Tech
Laser Safety Committee LSC
The LSC establishes and maintains safety policies procedures and guidance regarding the
use of class 3B and 4 lasers at Georgia Tech The LSC considers and advises EHS and IC
EHS on programs and policies regarding the safe and compliant use of class 3B and 4
Lasers at Georgia Tech
Laboratory Responsibilities
Deans are responsible for communicating the performance expectation to Department Chairs
and Principal Investigators PIs that the practices and policies set forth in this manual are to
be adhered to in all laboratories within their respective Colleges Deans are responsible for
setting the overall tone regarding establishing and maintaining a culture of safety in all
laboratory operations under their control Safety performance expectations must be clearly
communicated to Department Chairs and PIs with the knowledge that disciplinary procedures
will be pursued against those who fail to implement safety practices or willfully disregard
safety practices and regulatory requirements
Georgia Institute of Technology
Laboratory Safety Manual
Department and School Chairs
Department and School Chairs are responsible for ensuring that the practices and policies set
forth in this manual are adhered to in all Georgia Tech laboratories under their control and
for communicating to lab personnel the expectation that a culture of safety is to be maintained
in all labs and within all lab groups Safety performance expectations must be clearly
communicated to laboratorians such as periodic self inspections and safety meetings prompt
corrective actions when safety deficiencies are identified and implementing disciplinary
procedures for those who fail to work safely or willfully disregard safety practices and
regulatory requirements
Principal Investigators PIs
PIs have the primary responsibility for controlling hazards and maintaining compliance with
applicable regulations and Georgia Tech policies in their laboratory ies This shall include
promoting a safety culture in the work place by ensuring that all faculty staff and students
are instructed in laboratory hazards and how to avoid them making safety discussions part of
lab meetings performing lab self inspections and ensuring that all lab users have received
the required safety training as described in Chapter 8 of this manual Additionally PIs are
responsible for controlling visitor outsider access to Controlled Unclassified Information and
Classified Information in laboratories see Chapters 11 and 15 for more information
Laboratory Users
Students staff and faculty shall be responsible for complying with oral and written safety
rules regulations and procedures required for the assigned task Students staff and faculty
lab users are responsible for bringing any safety issues to the attention of the PI for
appropriate corrective action
Environmental Health Safety EHS
EHS is responsible for guiding and assisting the Institute community in meeting its public
health safety environmental protection and compliance responsibilities EHS shall assist PIs
and laboratory users in determining and following safe practices coordinating safety
activities providing education in safety investigating accidents and incidents in laboratories
and chemical incidents campus wide conducting lab inspections and verifying proper
operation of lab safety equipment and systems While lab safety programs are most effective
when lab groups self monitor and enforce the rules EHS is also responsible for monitoring
and verifying compliance with state and federal safety regulations and Georgia Tech lab
safety policies In cases of imminent danger to life and health of individuals working in the
laboratory and or others nearby EHS is authorized to take appropriate action including but
not limited to stopping work closing the laboratory and evacuating laboratories or buildings


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